Quiz: What major event in the 1930s significantly impacted the eco March 2, 2025 by Bennett Ridge What major event in the 1930s significantly impacted the economy and culture of the Appalachian region? Discover more about Appalachian Tours at our home page. A) The Great Depression B) The establishment of the Civilian Conservation Corps C) The introduction of coal mining regulations D) The founding of the Appalachian Trail Submit Answer